Anti-tumor相关论文
Probing the new strategy for the oral formulations of taxanes:changing the method with the situation
The first-generation taxanes(including paclitaxel and docetaxel)are widely used for the treatment of various cancers in ......
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The present study was designed to determine the chemical constituents of the stem tuber ofPinellia pedatisecta.The chemi......
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Objective In many years of research,the role of aspirin in a variety of diseases has been discovered,from the beginning ......
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Design,synthesis and preliminary biological evaluation of pyrrolidine derivatives as Mcl-1 inhibitor
The B-cell lymphoma(Bcl-2)family proteins are potential targets for cancer treatment.In our studies,a series of pyrrolid......
Studying on the medicinal value and the SAR of natural compounds and their derivatives is one of the most important meth......
Chalcone,which exist in the Kava plant[1] aroused considerable interest recently for their various bioactivities,includi......
Design synthesis and anti-tumor activities of novel salicylamide derivatives as potential anti-tumor
In recent years,the development of EGFR inhibitors focuses on ATP competitive inhibitors,and many small molecules includ......
OBJECTIVE To investigate the effect of recombinant toxin protein rLj-RGD from Lampetra japonica (RGD) on growth and meta......
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Bioreducible cross-linked hyaluronic acid/calcium phosphate hybrid nanoparticles for specific delive
Stimuli-responsive delivery systems have been increasingly ultilized to promote physiological specificity and on-demand ......
Discovery of diaryl-1,2,4-triazoles bearing caffeic acid analogs as dual inhibitors of cyclooxygenas
Studies regarding the relationship between AA metabolic process and carcinogenesis revealed the novel molecular target f......
The pyrazolidine-3,5-diones,as an important heterocyclic compounds,have represent excellent biological activities such a......
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Galactose-specific PEGylated PHDCA nanoparticles for active Norcantharidin delivery in hepatocellula
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Objective: To investigate the anti-tumor effect of γδ T cells on gastric adenocarcinoma SGC-7901 at cellular level in ......
[Objective]The study aimed to further explore the functional properties of Chinese wild blueberry.[Methodsl Anthocyanins......
Tumor-associated carbohydrate antigens(TACAs)are regarded as important targets for vaccine development.Vaccines based on......
We propose a modular synthesis strategy to constitute metallosalphen prodrugs in the form of coordination polymer nanopa......
Wogonin (5,7-dihydroxy-8-methoxyflavone, WG, Fig.1) is an attractive candidate for the development of new anti-cancer dr......
ObjectiveTo study isomalabaricane triterpenes with anti-tumor activities from the marine sponge Stelletta tenuis Lindgre......
Aim: To get enough quantity and quality of DL1106 and its analogue to evaluate their anti-tumor activity, the fermentati......
Aims: To investigate the in vitro and in vivo anti-tumor effect of Pulsatilla saponins,the major components extracted fr......
Aim: To study the anti-tumor effect of three kinds of traditional chinese medicine(TCM) and discuss the mechanisms about......
Discovery and evaluation of non-ATP competitive inhibitors of fibroblast growth factor receptor 1 wi
The fibroblast growth factor receptor tyrosine kinases (FGFR1) represent promising therapeutic targets in a number of ca......
AIM Daphnoretin is a bicoumarin compound isolated from natural product, which is used to treat many diseases in the hist......
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Nitric oxide (NO) is a kind of low molecular weight endogenous signaling molecule which was well-known as "Molecule of ......
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Context Custard apple (Annona squamosa Linn.) is an edible tropical fruit, and its seeds was used to treat "malignant s......
Formation and Stabilization of The Human Telomeric Repeats-Containing RNA G-quadruplex by Benzothiox
Telomere DNA is transcribed into telomeric repeat-containing RNA(referred to as TERRA)in mammalian cells....
The anti-tumor effects of flavonoids from the ethnic medicine Docycia delavayi (Franch.) Schneid.and
Docycia delavayi (Franch.) Schneid., a Chinese Dai ethnic medicine popularly known as "Duoyi" in Yunnan province of Ch......
5-O-methylvisammioside is a chemical derived from the dry root of Saposhnikovia divaricata,which has the functions of ex......
CoMFA Model of Anti-tumor Activity for Fluoroquinolon-3-yl s-Triazole Sulfide-ketone Derivatives and
Comparative molecular field analysis(CoMFA)techniques were used to perform three-dimensional quantitative structure-acti......
Psoriasis is a chronic, immune-mediated, inflammatory disease with a high prevalence in the general population (2%). The......
Memory CD8 T cells can provide long-term protection against tumors,which depends on their enhanced proliferative capacit......
A statin is a cholesterol-lowering agent,which inhibits HMG-CoA(3-hydroxy-3-methylglutaryl-coenzyme A)reductase and subs......
Tumor-associated carbohydrate antigens (TACAs) are regarded as important targets for vaccine development.1 Vaccines base......
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The multitarget anti-tumor effects of Ganoderma lucidum(G.lucidum) is reviewed by data from our laboratory and refer......
为了探讨旋毛虫A200711蛋白对BALB/c裸鼠皮下人肝癌H7402细胞实体瘤的抑制作用。本试验将BALB/c裸鼠右侧腋下注射人肝癌H7402细胞,......
Study on the interactions between anti-tumor metal complexes and mononucleotides using trans-[en2Os(
The interaction of several anti-tumor metal complexes with dGMP have been investigated using trans-[en2Os(η2-H2)]2+ as ......
为研究一种全人源抗VEGF单克隆抗体在体外和体内的抑制血管生成和抗肿瘤活性,利用细胞划痕实验检测抗体抑制人脐静脉内皮细胞(HUVE......
恶性肿瘤发病率逐年升高,已严重威胁人类身体健康发展,目前抗癌药物的作用多为非特异性,多存在严重对机体不利的不良反应。茶叶提......
Traditionally, the materials which are regarded as antigens recognized by γδ T lymphocytes are protein and carbohydrat......
熊果酸广泛分布在天然植物中,具有抗肿瘤活性.近几十年的研究表明,它可以通过抑制肿瘤形成及细胞毒作用、抑制肿瘤细胞增殖、诱导......
